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The -cyano amide-based Michael acceptors have also been elegantly used by the Taunton group as warheads in small-molecule inhibitors to react with active site cysteines while being minimally affected by the high concentration of intracellular GSH due to the fast reaction kinetics and the mM of K d (refs 31, 32)

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Your healthcare provider will initiate treatment at a low dose and gradually escalate over several weeks to minimize gastrointestinal side effects

References PubChem search: AHK copper peptide PubMed: Ala-His-Lys copper peptide PubMed: copper peptides and extracellular matrix Research-use notice: Supplied strictly for lawful research, laboratory, analytical, educational, or R&D purposes where permitted by applicable law